EpiFluid Lab

Epigenomics & Liquid Biopsy


We are epigenomics and computational biology lab within the Division of Human Genetics in the Cincinnati Children’s Hospital Medical Center (CCHMC) and also part of the Department of Pediatrics in University of Cincinnati College of Medicine.


The focus of the lab is on developing and applying machine learning and high-throughput experimental methods to understand the gene regulation and non-coding genetic variants. Specifically, we would like to understand the multi-omics heterogeneity in circulating cell-free DNA, exosomal DNA and its related cell types to explore the role of epigenetics in gene regulation and therefore bridge the gap between genetic and phenotypic variations at different healthy and pathological conditions.

Recent news

Dr. Yaping Liu received Trustee Award from Cincinnati Children’s Research Foundation for cell-free DNA work